Alzheimer's & Dementia Weekly: Off-Label

Showing posts with label Off-Label. Show all posts

Tuesday, January 10

Quadrupling Donepezil (Aricept)

MEDICATION: THE WORLD'S MOST POPULAR DEMENTIA-DRUG IS DONEPEZIL. Donepezil (Brand-name: Aricept®) boosts memory & thinking in Alzheimer's. More donepezil means more boost - along with intensified side-effects. Learn how it can be safely boosted when combined with solifenacin.

Antibiotics Weaken Alzheimer's

DRUGS: Long-term antibiotic treatment decreased Alzheimer's-causing plaques in the lab. It also helped the brain fight inflammation by enhancing the neuroinflammatory activity of microglial cells. Learn how.

Cognitive Boost for Dementia with Lewy Bodies

GOOD NEWS: Donepezil (Aricept^®), approved for Alzheimer's, also passed a long-term trial for Dementia with Lewy Bodies (DLB). Get the details on the medicine's positive results.

Memantine Improves Lewy Body Dementia & Parkinson's

Namenda / Memantine (Photo: Forrest Pharmaceutical)

OFF-LABEL MEDICATIONS:

Memantine (Namenda / Ebixa) is FDA-approved for Alzheimer's. Learn how it significantly improves memory and attention in Lewy Body Disease, Parkinson's and various types of dementia.

Felodipine, FDA-Approved for Blood Pressure, Shows Promise in Dementia

OFF-LABEL: An approved prescription drug for high blood pressure is showing promise against Parkinson's, Huntington's and other forms of dementia, in experimental studies in the lab.

At War With Alzheimer's: Testing 126 New Drugs

126 DRUGS ARE IN ALZHEIMER'S clinical trials. "Every single one represents hope," according to Closing in on a Cure: Alzheimer's Clinical Trials Report. Read the report. Learn about the trials.

3 FDA-Approved Drugs Show Promise in Fighting Alzheimer's: Fujimycin, Ciclosporin & Rapamycin

In the lab, fujimycin slowed Alzheimer's. (Fujimycin is an organ-transplant drug also called FK506 or Tacrolimus.) In past studies, similar drugs, like rapamycin and ciclosporin, also lowered rates of Alzheimer's. Learn how these immunosuppressants show great promise in the fight against Alzheimer's.

Levetiracetam Normalizes Alzheimer's Brain Activity

DRUG RESEARCH VIDEO + ARTICLE:

This FDA-approved anti-epileptic medication benefits Alzheimer's in the lab. Learn about the promising research.

Glutathione Peroxidase Defends Against Huntington's Dementia

Geneticists have discovered a promising direction in Huntington's treatment. In the lab, glutathione peroxidase improved Huntington's disease. Drugs mimicking this activity are already approved for other disorders. Learn about this new approach to treat people with Huntington's.

Alzheimer's Agitation: Citalopram May Help

MEDICATION & TREATMENT VIDEO:

Agitation is one of the most common symptoms of Alzheimer’s. See why citalopram may be effective in alleviating Alzheimer's agitation and aggression.

Alzheimer's Drugs: Risky for Other Memory Problems?

MEDICATION:

New insights in using Alzheimer's drugs for other memory problems shows why these medications are no simple memory patch.

Arginine Deprivation: The Alzheimer's Trigger?

REVIEW - PROGRESS THROUGH RESEARCH - VIDEO & ARTICLE:

Alzheimer's may be triggered by brain immune-system imbalances. Learn the way Duke University researchers want to re-balance that system. See how the nutrient arginine affects memory.

Alzheimer's Agitation Reduced by Dextromethorphan-Quinidine Pill

MEDICATION & MOOD:

Aggression and agitation are hard challenges in dementia. An important study may offer some simple answers.

Nilvadipine Increases Bloodflow to Brain in Alzheimer's

OFF-LABEL DRUGS, VIDEO & ARTICLE: The American Heart Association reports the blood pressure drug nilvadipine increases blood flow to the brain's memory and learning center. It does so without affecting other areas of the Alzheimer's brain. This indicates that decreased blood-flow in the Alzheimer's brain can be reversed in important regions.