Magnesium's Importance to Brain Health

DIET: MAGNESIUM appears to do more to maintain brain health, prevent cognitive impairment (CI), and fight Alzheimer's Disease (AD), than previously thought. Learn how.

---

The results of one medically significant study spearheaded by Dr. Guosong Liu, one of the world's leading cognitive health researchers, suggest that elevation of brain magnesium through dietary intake of magnesium threonate exerts substantial positive effects on brain synapes in a mouse model of AD, actually restoring aging brains to their youthful conditions. The study is the first to show a mechanism for reversing cognitive decline in advanced stage AD mice, and is also the first to show an effective long-term treatment in AD mice.* More exciting, though, are the implications of this study for the potential for treating AD in humans.

Dramatic Effects on Memory & Synapses in the Lab

Commenting on his work, Dr. Liu said, "The body of our peer-reviewed and published work underscores that magnesium threonate can help maintain healthy brain activity. There is no doubt that magnesium threonate has dramatic effects in preventing synapse loss and reversing memory decline in mice with Alzheimer's disease.

Furthermore, he states, "There is no question that cognitive impairment is a major fear and health issue for the nation. People are living longer and they want to take steps to maintain the quality of their physical and mental health. Cognitive impairment can affect a person's memory, language, perception, ability to plan and carry out tasks, and judgment. A recently concluded double blind, placebo-controlled human study, the 'gold standard' of science, demonstrates that dietary supplementation of ... magnesium threonate, can significantly enhance human cognitive functions and decrease symptoms of cognitive impairments." The study is expected to be published in a leading peer-reviewed journal in 2014.

Dr. Peter Osborne, a Board Certified doctor of clinical nutrition, said, "Healthy cognitive function begins with a solid nutritional foundation. We know magnesium is essential to maintaining healthy brain functions. We know 50 million Americans are magnesium deficit because people do not eat enough foods that contain magnesium. We know that as we age our bodies naturally lose magnesium. For example, drinking coffee or caffeinated products increases the loss. This deficit must be replaced by taking a nutritional supplement."

How Much Magnesium is Healthy?

Recommended Dietary Allowances (RDAs) for Magnesium ^[1]

Age	Male	Female	Pregnancy	Lactation
Birth to 6 months	30 mg*	30 mg*
7–12 months	75 mg*	75 mg*
1–3 years	80 mg	80 mg
4–8 years	130 mg	130 mg
9–13 years	240 mg	240 mg
14–18 years	410 mg	360 mg	400 mg	360 mg
19–30 years	400 mg	310 mg	350 mg	310 mg
31–50 years	420 mg	320 mg	360 mg	320 mg
51+ years	420 mg	320 mg

*Adequate Intake (AI)

Sources of Magnesium

Food

Magnesium is widely distributed in plant and animal foods and in beverages. Green leafy vegetables, such as spinach, legumes, nuts, seeds, and whole grains, are good sources ^[1,3]. In general, foods containing dietary fiber provide magnesium. Magnesium is also added to some breakfast cereals and other fortified foods. Some types of food processing, such as refining grains in ways that remove the nutrient-rich germ and bran, lower magnesium content substantially ^[1]. Selected food sources of magnesium are listed in Table 2.

Tap, mineral, and bottled waters can also be sources of magnesium, but the amount of magnesium in water varies by source and brand (ranging from 1 mg/L to more than 120 mg/L) ^[8].

Approximately 30% to 40% of the dietary magnesium consumed is typically absorbed by the body ^[2,9].

Selected Food Sources of Magnesium ^[10]

Food	Milligrams (mg) per	Percent DV*
Almonds, dry roasted, 1 ounce	80	20
Spinach, boiled, ½ cup	78	20
Cashews, dry roasted, 1 ounce	74	19
Peanuts, oil roasted, ¼ cup	63	16
Cereal, shredded wheat, 2 large biscuits	61	15
Soymilk, plain or vanilla, 1 cup	61	15
Black beans, cooked, ½ cup	60	15
Edamame, shelled, cooked, ½ cup	50	13
Peanut butter, smooth, 2 tablespoons	49	12
Bread, whole wheat, 2 slices	46	12
Avocado, cubed, 1 cup	44	15
Potato, baked with skin, 3.5 ounces	43	11
Rice, brown, cooked, ½ cup	42	11
Yogurt, plain, low fat, 8 ounces	42	11
Breakfast cereals, fortified with 10% of the DV for magnesium	40	10
Oatmeal, instant, 1 packet	36	9
Kidney beans, canned, ½ cup	35	9
Banana, 1 medium	32	8
Salmon, Atlantic, farmed, cooked, 3 ounces	26	7
Milk, 1 cup	24–27	6–7
Halibut, cooked, 3 ounces	24	6
Raisins, ½ cup	23	6
Chicken breast, roasted, 3 ounces	22	6
Beef, ground, 90% lean, pan broiled, 3 ounces	20	5
Broccoli, chopped and cooked, ½ cup	12	3
Rice, white, cooked, ½ cup	10	3
Apple, 1 medium	9	2
Carrot, raw, 1 medium	7	2

The U.S. Department of Agriculture's (USDA's) Nutrient Database Web site ^[10] lists the nutrient content of many foods and provides a comprehensive list of foods containing magnesium.

• See magnesium & other brain-healthy supplements on Amazon.com.

See Recipe:

• Magnesium-Rich Pumpkin Pie

Sources:

1. AIDP.
2. 

---

Reference:

1. W. Li, J. Yu, Y. Liu, X. Huang, N. Abumaria, Y. Zhu, X. Huang, W. Xiong, C. Ren, X.-G. Liu, D. Chui, G. Liu. Elevation of Brain Magnesium Prevents and Reverses Cognitive Deficits and Synaptic Loss in Alzheimer's Disease Mouse Model. Journal of Neuroscience, 2013; 33 (19): 8423 DOI: 10.1523/JNEUROSCI.4610-12.2013